The Importance of Early Improvement in Depressive Episodes

In patients with major depressive disorder (MDD), how are symptomatic remission and functional outcomes related?

a. Achievement of remission and improvements in functional outcomes occur at the same time.

b. Achievement of remission often occurs before improvements in functional outcomes are seen.

c. Improvements in functional outcomes occur before achievement of remission.

d. There is often no temporal relationship between the two.

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